Prospective clinical evaluation of fluorescence imaging in positively predicting the presence of Pseudomonas aeruginosa in chronic wounds

January 27, 2020 -ABSTRACT Aim:

Real-time, point-of-care detection of critical bacterial colonization relies primarily on subjective visual inspection and clinical signs and symptoms. When wounds are illuminated by violet light, most pathogenic bacterial species emit a unique red fluorescence signal due to the production of endogenous porphyrins, while Pseudomonas aeruginosa uniquely emits

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Point-of-care fluorescence imaging predicts the presence of pathogenic bacteria in wounds: a clinical study

August 2, 2017 -ABSTRACT Objective:

Bacteria in chronic wounds are invisible to the naked eye and can lead to delayed wound healing. Point-of-care bacterial fluorescence imaging illuminates a wound with 405 nm light, triggering bacteria to produce red fluorescence and enabling real-time bacterial localization. Prospective, single-blind clinical trials (clinicaltrials.gov #NCT02682069,#NCT03091361) were conducted to

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New horizons in the understanding of the causes and management of diabetic foot disease: report from the 2017 Diabetes UK Annual Professional Conference Symposium

January 23, 2017 -ABSTRACT

Diabetes-related foot disease remains a common problem. For wounds, classic teaching recommends the treatment of any infection, offloading the wound and ensuring a good blood supply, as well as ensuring that the other modifiable risk factors are addressed and optimized. There remain, however, several questions about these and other

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