Optimize Pseudomonas aeruginosa treatment with the MolecuLight i:X

January 27, 2020 -Clinician used MolecuLight i:X to confirm the presence and location of Pseudomonas aeruginosa in a venous leg ulcer. As seen in Figure 3, the white/cyan color suggests heavy levels of Pseudomonas aeruginosa pre-debridement (the white/cyan color is due to signal oversaturation), which would otherwise be invisible to the unaided eye. The clinician uses this information to guide debridement of bioburdened tissue and re-imaged the wound post-debridement. Figure 4 indicates a reduction in bioburden post-debridement, but not the eradication of Pseudomonas aeruginosa. Read More

Handheld real-time fluorescence imaging of bacteria guides treatment selection and timing of dressing changes in inpatients undergoing negative pressure wound therapy

January 27, 2020 -ABSTRACT Aim:

Knowledge of wound bioburden can help guide selection of optimal therapies, for example, negative pressure wound therapy devices (NPWT) with instillation of wound cleansers in a heavily contaminated wound. Fluorescence imaging can visualize red-fluorescing, pathogenic bacteria in real-time using a non-contact, hand held device.1 We used this

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Point-of-care fluorescence imaging predicts the presence of pathogenic bacteria in wounds: a clinical study

August 2, 2017 -ABSTRACT Objective:

Bacteria in chronic wounds are invisible to the naked eye and can lead to delayed wound healing. Point-of-care bacterial fluorescence imaging illuminates a wound with 405 nm light, triggering bacteria to produce red fluorescence and enabling real-time bacterial localization. Prospective, single-blind clinical trials (clinicaltrials.gov #NCT02682069,#NCT03091361) were conducted to

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Improved detection of clinically relevant wound bacteria using autofluorescence image-guided sampling in diabetic foot ulcers

February 28, 2017 -ABSTRACT

Clinical wound assessment involves microbiological swabbing of wounds to identify and quantify bacterial species, and to determine microbial susceptibility to antibiotics. The Levine swabbing technique may be suboptimal because it samples only the wound bed, missing other diagnostically relevant areas of the wound, which may contain clinically significant bacteria.

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