Improved detection of clinically-relevant wound bacteria using autofluorescence image-guided sampling in diabetic foot ulcers

January 27, 2020 -ABSTRACT Aim:

To compare the efficacy of standard clinical signs and symptoms (CSS) guided-Levine swabbing with autofluorescence (AF) imaging-guided swabbing to detect bacteria in diabetic foot ulcers.


Twenty-nine participants with diabetic foot ulcers were recruited between December 2014 and February 2015. Diabetic foot ulcers (n=31) were evaluated for CSS

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Clinical evaluation of fluorescence imaging in positively predicting the presence of bacteria in chronic wounds at the point of care

January 27, 2020 -ABSTRACT Background:

Clinical diagnosis of infection in chronic wounds involves assessment of signs and symptoms based on visual inspection and microbiological cultures. This process is subjective and delayed culture results often prevent prompt treatment. Fluorescence imaging has recently been introduced as a new method to visualize the presence of

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Point-of-care fluorescence imaging predicts the presence of pathogenic bacteria in wounds: a clinical study

August 2, 2017 -ABSTRACT Objective:

Bacteria in chronic wounds are invisible to the naked eye and can lead to delayed wound healing. Point-of-care bacterial fluorescence imaging illuminates a wound with 405 nm light, triggering bacteria to produce red fluorescence and enabling real-time bacterial localization. Prospective, single-blind clinical trials ( #NCT02682069,#NCT03091361) were conducted to

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Improved detection of clinically relevant wound bacteria using autofluorescence image-guided sampling in diabetic foot ulcers

February 28, 2017 -ABSTRACT

Clinical wound assessment involves microbiological swabbing of wounds to identify and quantify bacterial species, and to determine microbial susceptibility to antibiotics. The Levine swabbing technique may be suboptimal because it samples only the wound bed, missing other diagnostically relevant areas of the wound, which may contain clinically significant bacteria.

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