More Accurate Wound Assessment Leads to Faster Wound Healing

Wound assessment is the first step in wound care and wound management and it can be challenging. Wound infection diagnosis currently relies on visual assessment of the wound under normal lighting conditions and clinical signs and symptoms which can be frustrating and lead to clinical failure.

But What If Clinicians Could See Bacteria In Wounds?

Bacteria are a key culprit in wounds that can lead to infection. The earlier clinicians can detect moderate/heavy levels of bacteria in wounds, the earlier they can act on it by determining the appropriate treatment and delivering optimum wound management and improved wound healing results.1

MolecuLight i:X™ For Wound Assessment

The MolecuLight i:X Imaging Device is a ground breaking development in wound assessment techniques making it possible for practitioners to screen wounds and streamline decision making on treatments and suitable interventions that can impact wound protocols and patient prognosis. The device has proven to be an important tool in personalizing wound assessment protocols and treatment options, tracking wound healing results and treatment efficacy to improve patient outcomes.1

References:
1: DaCosta RS et al; Point-of-care autofluorescence imaging for real-time sampling and treatment guidance of bioburden in chronic wounds:first-in-human results. PLOS one, February 2015.

How MolecuLight i:X Guides Clinicians During Wound Assessment

1. Identify Presence of Bacteria in Real-time

MolecuLight i:X assists in locating and removing bacteria prior to application of treatments contraindicated or less effective when bacteria is present.

Patient #1

A male patient with diabetic foot ulcer was treated at Judy Dan Research & Treatment Center, Toronto, ON.

Clinician detected presence of moderate/heavy levels of bacteria with MolecuLight i:X (Figure 2). Microbiological analysis confirmed to be Staphylocccus aureus.

Diabetic Foot Ulcer - Patient #1

Figure 1: ST-imageTM. Picture taken under normal lighting conditions.
Figure 2: FL-imageTM. Picture taken with MolecuLight i:X in Fluorescence Imaging ModeTM. The red color indicates presence of moderate/heavy levels of bacteria. Culture test result proved to be Staphylocccus aureus.

2. Guide Sampling

MolecuLight i:X guides sampling in areas where bacteria are known to be present and ensures the correct areas are sampled so that results more accurately represent the true bacterial load.

Patient #2

Patient was imaged at the Judy Dan Research and Treatment Centre in Toronto, Canada as part of a non-randomized, concurrent (subject as own) control clinical trial. The MolecuLight i:X was used as an adjunctive tool in the assessment of the wound and was used to guide the targeted sampling of a wound (with a swab - Figure 4) so as to compare it to gold standard swabbing (Levine technique - Figure 3).2

The culture test result of the swab guided by i:X confirmed presence of heavy growth of mixed bacteria while the sample test result of the swab done under normal lighting conditions showed no presence of bacteria.

Diabetic Foot Ulcer - Patient-#2

Figure 3: ST-imageTM. Picture taken under normal lighting conditions. The white circle indicates where a swab sample was obtained according to the Levine technique. The Culture test result showed no presence of bacteria.
Figure 4: FL-imageTM. Picture taken with MolecuLight i:X in Fluorescence Imaging ModeTM. The red color indicates presence of moderate/heavy levels of bacteria. The white circle indicates where a swab sample was obtained according to MolecuLight i:X guidance. The Culture test result confirmed presence of heavy growth of mixed bacteria.

 

References:
2: Clinical trial registration on clinicaltrials.gov NCT02315092.

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